Plenary Speakers Hermona Soreq, PhD Affiliation: The Edmond & Lily Satra Center for Brain Sciences, Jerusalem (Israel) Title: Capturing alternative splicing patterns in the human degenerating brain Thomas Cooper, PhD Affiliation: Baylor College of Medicine (USA) Title: Alternative splicing regulatory networks in development and their disruption in disease Francisco Baralle, PhD Affiliation: International Center for Genetic Engineering and Biotechnology, RNA Biology Group, Padriciano 99, Trieste (Italy) Title: TDP 43 self regulation, aggregation and neurodegeneration onset Benoit Chabot, PhD Affiliation: Département de microbiologie et d’infectiologie, Faculté de médecine et des sciences de la santé, Univesite de Sherbrooke (Canada) Title: Connecting DNA damage with splicing decisions David Bates, PhD Affiliation: Division of Cancer and Stem Cells School of Medicine, University of Nottingham, Nottingham (UK) Title: Development of alternative splicing regulators as novel therapeutics